Microbiology Notes By Sagar Aryal
Structure of Human Cytomegalovirus Figure: Structure of Human Cytomegalo Virus, Source: Dr. Marko Reschke, Marburg, Germany Cytomegalovirus is a member of the herpes virus family that falls under the beta herpes subfamily. CMV is spherical in shape with icosahedral symmetry. The icosahedral protein capsid with an average diameter of 100 nm consists of 162 hollow … Read more Human Cytomegalovirus
Measles Virus Image Source: BBC Structure Measles virus is the prototypic member of the Morbillivirus genus of the family Paramyxoviridae. Measles virus is spherical with a diameter ranging from 120 to 1000 nm and has two major structural components: one is the helical ribonucleoprotein (RNP) core formed by the association of the nucleoprotein (N), phosphoprotein … Read more Measles Virus
Structure of Coronavirus Coronaviruses fall in the virus family Coronaviridae, order Nidovirales. Coronaviruses are enveloped, 120 to 160 nm particles that contain an unsegmented genome of single-stranded positive-sense RNA (27–32 kb). The large, plus-stranded RNA genome associates with the N protein to form a helical nucleocapsid. The helical nucleocapsid is 9–11 nm in diameter. There are … Read more Coronavirus
Varicella Zoster Virus Structure of Varicella Zoster Virus Image Source: Creative Diagnostics Varicella-zoster virus (VZV) is an alphaherpesvirus that is in the same subfamily as herpes simplex virus (HSV) 1 and 2. VZV is a member of varicellovirus genus. The virion is spherical in shape with icosahedral symmetry measuring 159-200nm. The icosahedral protein capsid with … Read more Varicella Zoster Virus
Oncogenic Viruses Viruses are the intracellular pathogens that reproduce only in the living cell and manipulate the cellular machinery to produce more viruses. Viral replications can affect cellular genes of the host in multiple cancerous ways. An oncovirus is a virus that can cause cancer. Viruses account for about 20% of total human cancer cases. Although many viruses can cause … Read more Oncogenic Viruses
Classification of virus Viruses are small obligate intracellular parasites, which by definition contain either a RNA or DNA genome surrounded by a protective, virus-coded protein coat. Viruses range from the structurally simple and small parvoviruses and picornaviruses to the large and complex poxviruses and herpesviruses. Viruses are classified on the basis of morphology, chemical composition, … Read more Classification of virus
Virus Cultivation- Purposes and Methods Viruses are obligate intracellular parasites so they depend on host for their survival. They cannot be grown in non-living culture media or on agar plates alone, they must require living cells to support their replication. The primary purposes of virus cultivation is: To isolate and identify viruses in clinical samples. … Read more Virus Cultivation- Purposes and Methods
Mumps Virus Structure of Mumps Virus Mumps virions are markedly pleomorphic (100 to 600 nm), and roughly spherical with an outer membrane that envelops an inner, coiled helical structure. The envelope which is 150 to 300nm is studded with projections formed by the viral glycoproteins that rise 12 to 15 nm from the virion surface. … Read more Mumps Virus
Herpes simplex virus 1 (HSV-1) Structure of Herpes simplex virus 1 (HSV-1) Herpesviruses are large (150-200 nm size), spherical in shape with icosahedral symmetry. The icosahedral protein capsid with average diameter 100 nm consists of 162 hollow hexagonal and pentagonal capsomeres with an electron-dense core containing the double stranded DNA genome with 125-240 kbp nucleotides … Read more Herpes simplex virus 1 (HSV-1)
Influenza A Virus Structure of Influenza A Virus Influenza A virus falls under the family Orthomyxoviridae. Influenza A virus particles are usually spherical and about 80- 120 nm in diameter. It is an enveloped virus and the envelope contains two glycoproteins, hemagglutinin (HA) and neuraminidase (NA), the membrane (M2) protein and is internally lined by the … Read more Influenza A Virus