Favipiravir- properties, uses, mechanism, side effects, COVID-19

Favipiravir

Medical Disclaimer: The information presented on this page is only for academic and study purposes and must not be used for the purpose of treatment. If you are not feeling well, please consult with your physician or doctor. What is Favipiravir? Favipiravir is an antiviral drug that was developed for the treatment of resistant influenza … Read more Favipiravir- properties, uses, mechanism, side effects, COVID-19

Dexamethasone- Properties, uses, side effects & COVID-19

Dexamethasone

Medical Disclaimer: The information presented on the website is only for academic and study purposes and must not be used for the purpose of treatment. If you are not feeling well, please consult with your physician or doctor. What is Dexamethasone? Dexamethasone is a corticosteroid that is widely used for the treatment of several diseases … Read more Dexamethasone- Properties, uses, side effects & COVID-19

Chloroquine (Chloroquine Phosphate)

Chloroquine (Chloroquine Phosphate)

Medical Disclaimer: The information presented on the website is only for academic and study purposes and must not be used for the purpose of treatment. If you are not feeling well, please consult with your physician or doctor. Update: FDA Revokes Emergency Use Authorization for Chloroquine and Hydroxychloroquine Introduction Chloroquine also is known as chloroquine … Read more Chloroquine (Chloroquine Phosphate)

Remdesivir- Mechanism of Action, Uses, Synthesis & COVID-19

Medical Disclaimer: The information presented on the website is only for academic and study purposes and must not be used for the purpose of treatment. If you are not feeling well, please consult with your physician or doctor. What is Remdesivir? Remdesivir is an antiviral drug that was developed by Gilead Sciences in 2014 as … Read more Remdesivir- Mechanism of Action, Uses, Synthesis & COVID-19

Hydroxychloroquine- uses, side effects, interactions & COVID-19

Hydroxychloroquine- uses, side effects, interactions & COVID-19

Medical Disclaimer: The information presented on the website is only for academic and study purposes and must not be used for the purpose of treatment. If you are not feeling well, please consult with your physician or doctor. Update: FDA Revokes Emergency Use Authorization for Chloroquine and Hydroxychloroquine What is hydroxychloroquine? Hydroxychloroquine is a drug … Read more Hydroxychloroquine- uses, side effects, interactions & COVID-19

Epsilometer test (E test)

Epsilometer test (E test)

Introduction Epsilometer test (E- test) is defined as the “exponential gradient” method that determines the antimicrobial resistance of the microorganism. It is a cost-effective tool that has been developed to provide a direct quantification of antimicrobial susceptibility of microorganisms. It is a quantitative method that applies both the dilution of antibiotics and the diffusion of … Read more Epsilometer test (E test)

In Silico drug designing and role of bioinformatics

drug designing

In Silico drug designing and role of bioinformatics “In Silico” is an expression used to mean “performed on computer or via computer simulation.”  In Silico drug designing is thus the identification of the drug target molecule by employing bioinformatics tools. The inventive process of finding new medications based on the knowledge of a biological target is called as drug designing. … Read more In Silico drug designing and role of bioinformatics

Methicillin Resistant Staphylococcus aureus (MRSA)

Methicillin Resistant Staphylococcus aureus (MRSA)

Methicillin Resistant Staphylococcus aureus (MRSA) MRSA is mediated by mecA gene; which is a chromosomally coded. It alters penicillin binding protein (PBP) present on S. aureus cell membrane to PBP-2a: PBP is an essential protein needed for cell wall synthesis of bacteria. β lactam drugs bind and inhibit this protein, there by inhibiting cell wall … Read more Methicillin Resistant Staphylococcus aureus (MRSA)

Beta-Lactamase and Ambler classification

Beta-Lactamase and Ambler classification

Beta-Lactamase and Ambler classification β-lactamase enzymes are capable of hydrolysing the β-lactam rings (the active site) of β-lactam antibiotics; thereby deactivating their antibacterial properties. It is observed in both gram-positive and gram-negative bacteria. They are plasmid coded, and transferred from one bacterium to other mostly by conjugation, (except in Staphylococcus aureus where they are transferred by … Read more Beta-Lactamase and Ambler classification

Beta (β)-Lactamase Test- Objectives, Principle, Procedure and Results

Result Interpretation of Beta (β)-Lactamase Test

Objective of Beta (β)-Lactamase Test To detect the enzyme beta-lactamase, which confers penicillin resistance to various bacterial organisms. Principle of Beta (β)-Lactamase Test Various bacteria produce a class of enzymes called beta-lactamases, which may be mediated by genes on plasmids or chromosomes. Production of beta-lactamase may be constitutive or induced by exposure to antimicrobials. Beta-lactamases hydrolyze (and thereby inactivate) … Read more Beta (β)-Lactamase Test- Objectives, Principle, Procedure and Results