Hepatitis A Virus- An Overview

Clinical Manifestations of Hepatitis A Virus

Structure of Hepatitis A Virus HAV (Hepatitis A Virus) is a distinct member of the picornavirus family, assigned to genus hepatovirus. HAV is a 27 nm to 32 nm spherical particle with icosahedral symmetry containing a linear single-stranded RNA genome with a size of 7.5 kb and non-enveloped. Hepatitis A virions have a primary buoyant density of 1.32 to 1.34 g/cc …

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Rotavirus- An Overview

Rota Virus- Structure, Genome, Epidemiology, Replication, Pathogenesis, Clinical Manifestation, Lab Diagnosis, Treatment, Vaccination, Prevention and Control

Structure of Rotavirus The name rotavirus is derived from the Latin word rota, meaning “wheel,” which refers to the virion’s appearance in negative-stained electron micrographs. Rotavirus falls under Reoviridae family and subfamily Sedoreovirinae, which appear more smooth, lacking the large surface projections. The virion has icosahedral symmetry and is triple-layered capsid lacking an envelope and measures 70–75 nm in diameter. …

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Rabies Virus- An Overview

Rabies Virus

Structure of Rabies Virus The virus is enveloped, rod shaped particles measuring 75 × 180 nm. Mature virion appears either as bullet shaped particles with one rounded and one flattened end or as bacilliform particles. The particles are surrounded by a membranous lipid envelope. The particles have a buoyant density in CsCl of about 1.19 g/cm3. The virion outer surface is …

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Hepatitis C virus- An Overview

Hepatitis C virus

Structure of Hepatitis C virus Hepatitis C virus (HCV) is a RNA virus belonging to the family Flaviviridae, genus Hepacivirus. The HCV virion is 55-65 nm in diameter containing in it a 9.6 kb positive sense single-stranded RNA genome composed of a long open reading frame (ORF) flanked by untranslated regions (UTR’s) at both the ends. The genome of HCV is …

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