Norwalk Virus (Norovirus)

Structure and Genome of Norwalk Virus

Structure of Norwalk Virus (Norovirus) The virus is non-enveloped, round, 27-nm particles with a ‘ragged’ outer edge but lacking a definite surface structure. It has buoyant density of 1.33–1.41 g/cm3, an inability to propagate in vitro. Characteristically, Norwalk virus possess a single capsid protein. The genome is a nonsegmented, single-stranded, positive polarity RNA genome. Ten prominent … Read moreNorwalk Virus (Norovirus)

Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)

Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)

Structure of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) They are enveloped viruses with round and sometimes pleiomorphic virions of approximately 80 to 120 nm in diameter. It contains positive-strand RNA, with the largest RNA genome (approximately 30 kb). The genome RNA is complexed with the basic nucleocapsid (N) protein to form a helical capsid found within … Read moreSevere Acute Respiratory Syndrome Coronavirus (SARS-CoV)

Ebola Virus

Ebola Virus- Structure, Genome, Epidemiology, Transmission, Replication, Pathogenesis, Clinical Manifestation, Lab Diagnosis, Treatment, Prevention and Control

Structure of Ebola Virus It falls under the Filoviridae family. The virion is filamentous, enveloped measuring 800 nm length and 80 nm in diameter. It comprises of negative sense, single stranded RNA genome. Structural proteins associated with the nucleocapsid are the nucleoprotein (NP), VP30, VP35, and the polymerase (L) protein. Membrane-associated proteins are the matrix protein … Read moreEbola Virus


Classification of Torovirus Group IV: ssRNA positive strand virus Order: Nidovirales Family: Coronaviridae Subfamily: Toronavirinae Genus: Torovirus Structure of Torovirus Torovirusis a genus of viruses in the order Nidovirales, in the family Coronaviridae, in the subfamily Torovirinae. Toroviruses are pleomorphic, enveloped particles, 120–140 nm in diameter. The virus particle has surface spikes proteins that are club-shaped 15 to 20 nm in length and … Read moreTorovirus

Hepatitis A Virus

Clinical Manifestations of Hepatitis A Virus

Structure of Hepatitis A Virus HAV (Hepatitis A Virus) is a distinct member of the picornavirus family, assigned to genus hepatovirus. HAV is a 27 nm to 32 nm spherical particle with icosahedral symmetry containing a linear single-stranded RNA genome with a size of 7.5 kb and non-enveloped. Hepatitis A virions have a primary buoyant density … Read moreHepatitis A Virus

Rota Virus

Rota Virus- Structure, Genome, Epidemiology, Replication, Pathogenesis, Clinical Manifestation, Lab Diagnosis, Treatment, Vaccination, Prevention and Control

Structure of Rota Virus The name rotavirus is derived from the Latin word rota, meaning “wheel,” which refers to the virion’s appearance in negative-stained electron micrographs. Rotavirus fall under Reoviridae family and subfamily Sedoreovirinae, which appear more smooth, lacking the large surface projections. The virion has icosahedral symmetry and is triple layered capsid lacking an envelope … Read moreRota Virus

Rabies Virus

Rabies Virus

Structure of Rabies Virus The virus is enveloped, rod shaped particles measuring 75 × 180 nm. Mature virion appears either as bullet shaped particles with one rounded and one flattened end or as bacilliform particles. The particles are surrounded by a membranous lipid envelope. The particles have a buoyant density in CsCl of about 1.19 g/cm3. … Read moreRabies Virus

Hepatitis C virus

Hepatitis C virus

Structure of Hepatitis C virus Hepatitis C virus (HCV) is a RNA virus belonging to the family Flaviviridae, genus Hepacivirus. The HCV virion is 55-65 nm in diameter containing in it a 9.6 kb positive sense single-stranded RNA genome composed of a long open reading frame (ORF) flanked by untranslated regions (UTR’s) at both the ends. … Read moreHepatitis C virus