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Instrumentation

Instrumentation is a collection of devices and mechanics used to measure, evaluate, and test systems.

  • In biology, the instrumentation is considered a part of biomedical engineering where the working mechanism and the parts of a system are studies.
  • Instrumentation in biology or Bioinstrumentation is primarily concentrated on bringing the engineering and medical worlds together.
  • Different devices like centrifuges and autoclaves that are common in biological laboratories are a part of the instrumentation. Studies done in instrumentations allow the understanding of the parts and working mechanisms of such devices.
  • Other important techniques include chromatography which is routinely performed in laboratories to separate biological systems, which are also equally important.
  • Instrumentation is still an emerging discipline with new pieces of machinery still being produced for convenience in laboratories.
  • The application of bio-instruments is not only limited to laboratories as modern agriculture makes use of bio-instruments to monitor and evaluate soil and to measure plant growth.
  • Besides, these instruments can also be used to determine the physiological activities of plants like the carbon dioxide trade rate, net photosynthesis, etc.
  • Processes like electrophoresis make use of nucleic acids along with biosensors to compare the DNA sequences. This enables genetic testing and diagnosis of various diseases.
  • Genetic testing is heavily influenced by the progress made in instrumentation as new devices and techniques are discovered which makes the process faster, more accurate, and more reliable.
  • As RT-PCR and blotting are considered advanced molecular diagnosis methods, disease diagnosis becomes faster and more accurate than ever. 
  • Determination of radioisotopes and concentration of a solution has been made easier with techniques like spectroscopy and colorimetry.
  • As the discipline continues to grow, the main focus of the field remains in the improvements of technology to make the medical processes faster and more efficient.
  • Instrumentation, thus, is slowly becoming an integral part of all biological fields with new emerging new technology and the discovery of fast and reliable procedures.

Affinity Chromatography- Definition, Principle, Parts, Steps, Uses

March 1, 2022January 3, 2022 by Sagar Aryal
Affinity Chromatography

What is Affinity Chromatography? Chromatography is an important biophysical technique that enables the separation, identification, and purification of the components of a mixture for qualitative and quantitative analysis. It is … Read more

Agarose Gel Electrophoresis- Definition, Principle, Parts, Steps, Applications

April 30, 2022January 2, 2022 by Sagar Aryal
Agarose Gel Electrophoresis

What is Agarose Gel Electrophoresis? Agarose gel electrophoresis is a method of gel electrophoresis used in biochemistry, molecular biology, genetics, and clinical chemistry to separate a mixed population of macromolecules such as DNA , RNA or proteins in … Read more

18 Instruments used in Microbiology Lab with Principle and Uses

December 2, 2021December 2, 2021 by Anupama Sapkota
Instruments used in Microbiology Lab with Principle and Uses

The instruments used in the microbiology labs include a bunch of different kinds of instruments required for a lot of different processes conducted within those laboratories. Figure: Instruments used in … Read more

Cell Disruption- Definition, Methods, Types, Significance

January 6, 2022October 10, 2021 by Sagar Aryal
Cell Disruption Methods

Cell disruption is the process of obtaining intracellular fluid via methods that open the cell wall. The overall goal in cell disruption is to obtain the intracellular fluid without disrupting … Read more

Bioreactor- Definition, Design, Principle, Parts, Types, Applications, Limitations

September 14, 2021September 7, 2021 by Sanjogta Thapa Magar
Bioreactor

Bioreactor Definition A bioreactor is a type of fermentation vessel that is used for the production of various chemicals and biological reactions. It is a closed container with adequate arrangement … Read more

Centrifugation- Principle, Types and Applications

July 27, 2021July 12, 2021 by Sagar Aryal
Centrifugation

Centrifugation is a technique of separating substances which involves the application of centrifugal force. The particles are separated from a solution according to their size, shape, density, the viscosity of the … Read more

Types of Centrifuge and Centrifugation (definition, principle, uses)

July 27, 2021July 10, 2021 by Anupama Sapkota
Types of Centrifuge and Centrifugation

Centrifuge definition A centrifuge is a device used to separate components of a mixture on the basis of their size, density, the viscosity of the medium, and the rotor speed. … Read more

Mass Spectrometry (MS)- Principle, Working, Instrumentation, Steps, Applications

March 22, 2021March 4, 2021 by Sagar Aryal
Mass Spectrometry (MS)

Mass Spectrometry (MS) Definition Mass Spectrometry (MS) is an analytical chemistry technique that helps identify the amount and type of chemicals present in a sample by measuring the mass-to-charge ratio … Read more

Ultracentrifuge- Definition, Principle, Types, Parts, Procedure, Uses

October 16, 2020 by Anupama Sapkota
Ultracentrifuge

Ultracentrifuge Definition Ultracentrifuge is a sophisticated and advanced centrifuge that operates at an extremely high speed and separates smaller molecules that cannot be separated from the traditional centrifuges. The speed … Read more

Laminar flow hood/cabinet- definition, parts, principle, types, uses

April 21, 2022October 1, 2020 by Anupama Sapkota
Laminar flow hood or cabinet

A Laminar flow hood/cabinet is an enclosed workstation that is used to create a contamination-free work environment through filters to capture all the particles entering the cabinet. These cabinets are … Read more

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