Online microbiology and biology related notes by SAGAR ARYAL
Homology Modeling- Working, Steps, and Uses Homology modeling is also known as comparative modeling predicts protein structures based on sequence homology with known structures. It is based on the principle that “if two proteins share a high enough sequence similarity, they are likely to have very similar three-dimensional structures.” It hence relies on the identification … Read moreHomology Modeling- Working, Steps, and Uses
Proteins- Properties, Structure, Classification and Functions Proteins are the most abundant biological macromolecules, occurring in all cells. It is also the most versatile organic molecule of the living systems and occur in great variety; thousands of different kinds, ranging in size from relatively small peptides to large polymers. Proteins are the polymers of amino acids … Read moreProteins- Properties, Structure, Classification and Functions
Four levels of hierarchy in protein conformation can be described. A. PRIMARY STRUCTURE PRIMARY STRUCTURE refers to the order of the amino acids in the peptide chain. 1. The free α-amino group, written to the left, is called the amino-terminal or N-terminal end. 2. The free α-carboxyl group, written to the right, is called the … Read moreProtein Structure- Primary, Secondary, Tertiary and Quaternary