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Immunology

Immunology is an emerging branch of medical science that deals with studies related to different aspects of the immune system like the cells, structure, function, response against antigens, and disorders.

  • The immune system consists of a collection of cells, chemicals, processes, and mechanisms that function to protect the body from foreign antigens, such as microbes (organisms such as bacteria, fungi, and parasites), viruses, cancer cells, and toxins.
  • Beyond, the structural and chemical barriers which protect us from infection, the immune system consists of two lines of defense; innate immunity and adaptive immunity.
  • The innate immunity represents the first line of defense against the antigen, and it is an antigen-independent defense mechanism used by the host immediately or within hours of encountering an antigen.
  • On the other hand, adaptive immunity is antigen-dependent and antigen-specific and, therefore, includes a lag time between exposure to the antigen and maximal response.
  • Studies conducted in immunology are related to the measurement of physiological functioning of the immune system in both healthy and disease conditions, malfunctioning of the system in the case of disorders, and physical, chemical, and physiological characteristics of the cells of the immune system.
  • Immunology is fast becoming an important branch of clinical medicine as it has a close relationship with organ transplantation, oncology, virology, bacteriology, and even dermatology.
  • Immunology is focused on certain organs of the body like the bone marrow and the lymphatic system and the white blood cells found in the blood.
  • These cells or organs producing these cells are responsible, directly or indirectly, for the defense mechanism of the body against a pathogenic agent or other antigens.
  • These cells keep on circulating throughout the body via blood or lymph so that they can detect antigens entering the body from different sources.
  • An important aspect of immunology is immunotherapy, where components of the immune system or antigens are used to treat a disease or disorder as a form of treatment.

Cells of Immune System- Types and Examples

May 20, 2022May 17, 2022 by Dr. Faith Mokobi
Cells of the immune system

The immune system is made up of different immune organs and tissues located all over the body. The immune organs are categorized based on their functions and there are two … Read more

ELISA- Definition, Principle, Procedure, Types, Steps, Uses

February 22, 2026May 17, 2022 by Bikash Dwivedi
ELISA Diagram

Enzyme-Linked Immunosorbent Assay (ELISA) is a modern molecular technique for the detection of antigen-antibody interaction with the help of an enzyme. It is one of the sensitive enzyme immunoassay techniques for the detection … Read more

Complement Fixation Test- Principle, Procedure, Results, Types

May 20, 2022May 17, 2022 by Bikash Dwivedi
Complement Fixation Test

Complements are some special chemicals or protein components that are a part of our humoral immunity and aid in establishing antigen-antibody complexes, engulfing, degrading, and washing them away. They are … Read more

Passive Immunity- Definition, Characteristics, Types, Examples

May 19, 2022May 16, 2022 by Dr. Faith Mokobi
Passive Immunity

Passive immunity is developed by antibodies that are produced outside and then introduced into the body. Passive immunity is acquired when antibodies are introduced into the body from an external … Read more

Active Immunity- Definition, Characteristics, Types, Examples

May 19, 2022May 16, 2022 by Dr. Faith Mokobi
Active Immunity

Active immunity develops due to the production of antibodies in the body. Active immunity is attained by exposure to a pathogen leading to the production of antibodies in the body. … Read more

Ouchterlony Double Immunodiffusion technique

September 5, 2022May 14, 2022 by Sagar Aryal, PhD
Ouchterlony Double Immunodiffusion technique

Immuno-diffusion is a technique for the detection or measurement of antibodies and antigens by their precipitation which involves diffusion through a substance such as agar or gel agarose. Simply, it … Read more

Antigen-Antibody Interaction- Definition, Stages, Types, Examples

May 20, 2022May 13, 2022 by Sagar Aryal, PhD
Antigen-Antibody-Interaction

Antigen-Antibody (Ag-Ab) Interaction is a biochemical reaction between antibodies and specific antigens when they come closer to a distance of several nanometers. It is the binding of paratopes of antibodies … Read more

Properties and Function of different classes of Antibodies

September 28, 2022May 12, 2022 by Sagar Aryal, PhD
Properties and Function of different classes of Antibodies

Antibodies are glycoproteins produced in membrane-bound or secreted form by B lymphocytes in response to exposure to foreign structures known as antigens. The human immunoglobulins are a family of proteins … Read more

Cytokines- Mechanism of action and Functions

September 5, 2022May 9, 2022 by Sagar Aryal, PhD
Cytokines- Mechanism of action and Functions

Cytokines Cytokines are a family of small proteins that mediate an organism’s response to injury or infection. Cytokines operate by transmitting signals between cells in an organism. Minute quantities of … Read more

Platelets (Thrombocytes)- Definition, Structure, Immunity, Functions

October 21, 2022May 5, 2022 by Anupama Sapkota
Platelets (Thrombocytes)

Platelets or thrombocytes are anucleated cells derived from the megakaryocytic cells in the bone marrow that, besides being one of the key players in maintaining hemostasis, are involved in developing … Read more

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