Enzyme Inhibition

Enzymes are the biological macromolecules, also called as biological catalysts, which speed up the rate of biochemical reactions without undergoing any change. It is a highly selective catalyst that greatly accelerates … Read more

Purine Synthesis

Purine Synthesis

There are two pathways of synthesis of purine nucleotides: De Novo synthesis pathway, and Salvage pathway. The De novo synthesis of Purine The de novo synthesis of purine nucleotide means … Read more

Cholesterol structure and synthesis

Cholesterol Synthesis

Cholesterol Structure Figure: Cholesterol Structure Although cholesterol is synthesized in most tissues of the body where it serves as a component of cell membranes, it is produced mainly in the … Read more

The Wobble Hypothesis

The Wobble Hypothesis

There are more than one codon for one amino acid. This is called degeneracy of genetic code. To explain the possible cause of degeneracy of codons, in 1966, Francis Crick … Read more

Pentose Phosphate Pathway

Pentose Phosphate Pathway

The pentose phosphate pathway is a metabolic pathway parallel to glycolysis which generates NADPH and pentoses (5-carbon sugars) as well as ribose 5-phosphate. The pentose phosphate pathway is also called as the phosphogluconate pathway or hexose monophosphate shunt. While it involves oxidation of glucose, its primary role … Read more

Urea Cycle- Enzymes and Steps

Urea Cycle- Enzymes and Steps

The urea cycle is the metabolic pathway that transforms nitrogen to urea for excretion from the body. Nitrogenous excretory products are removed from the body mainly in the urine. Ammonia, … Read more