Sagar Aryal, PhD 
Restriction Enzyme (Restriction Endonuclease) Definition Restriction enzyme, also called restriction endonuclease, is a protein produced by bacteria that cleaves DNA at specific sites along the molecule. Restriction endonucleases cut the DNA double helix in very … Read more
Nucleotide is any member of the class of organic compounds in which the molecular structure comprises a nitrogen-containing unit (base) linked to a sugar and a phosphate group. They are monomeric units of nucleic … Read more
DNA microarrays are solid supports, usually of glass or silicon, upon which DNA is attached in an organized, pre-determined grid fashion. Each spot of DNA, called a probe, represents a … Read more
Structure of Polio Virus Poliovirus is a member of a family of viruses called the Picornaviridae. Virions are spherical in shape with a diameter of about 27nm. The particles are simple … Read more
Structure of Japanese Encephalitis (JE) Virus Japanese encephalitis (JE) virus falls under the family Flaviviridae. The particles appear to be spherical, 50 nm in diameter, containing an electron dense core (about … Read more
Structure of Hepatitis E Virus Image: Schematic illustration of non-enveloped and quasi-enveloped HEV particles as well as enveloped virus. The putative model of quasi-enveloped HEV virion includes ORF3 product in its … Read more
What is an Autoimmune disease? Autoimmune disease occurs when a specific adaptive immune response is mounted against self-antigens. The normal consequence of an adaptive immune response against a foreign antigen … Read more
Restriction Fragment Length Polymorphism (RFLP) is a technique in which organisms may be differentiated by analysis of patterns derived from cleavage of their DNA. It is a technique that exploits … Read more
Principle of RPR Test The Rapid Plasma Reagin tests are macroscopic, non-treponemal flocculation card test that detect antibodies produced against antigens released by damaged host cells in patients suffering from syphilis. In … Read more
Latex Agglutination Test A group of passive agglutination tests carried out by coating either antigen or antibody on an artificial carrier particle, called latex bead are called as latex agglutination … Read more
