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Immunology

Immunology is an emerging branch of medical science that deals with studies related to different aspects of the immune system like the cells, structure, function, response against antigens, and disorders.

  • The immune system consists of a collection of cells, chemicals, processes, and mechanisms that function to protect the body from foreign antigens, such as microbes (organisms such as bacteria, fungi, and parasites), viruses, cancer cells, and toxins.
  • Beyond, the structural and chemical barriers which protect us from infection, the immune system consists of two lines of defense; innate immunity and adaptive immunity.
  • The innate immunity represents the first line of defense against the antigen, and it is an antigen-independent defense mechanism used by the host immediately or within hours of encountering an antigen.
  • On the other hand, adaptive immunity is antigen-dependent and antigen-specific and, therefore, includes a lag time between exposure to the antigen and maximal response.
  • Studies conducted in immunology are related to the measurement of physiological functioning of the immune system in both healthy and disease conditions, malfunctioning of the system in the case of disorders, and physical, chemical, and physiological characteristics of the cells of the immune system.
  • Immunology is fast becoming an important branch of clinical medicine as it has a close relationship with organ transplantation, oncology, virology, bacteriology, and even dermatology.
  • Immunology is focused on certain organs of the body like the bone marrow and the lymphatic system and the white blood cells found in the blood.
  • These cells or organs producing these cells are responsible, directly or indirectly, for the defense mechanism of the body against a pathogenic agent or other antigens.
  • These cells keep on circulating throughout the body via blood or lymph so that they can detect antigens entering the body from different sources.
  • An important aspect of immunology is immunotherapy, where components of the immune system or antigens are used to treat a disease or disorder as a form of treatment.

Phagocytosis- definition, mechanism, steps with example

June 27, 2022May 1, 2022 by Sagar Aryal, PhD
Phagocytosis- Introduction, Mechanism, Steps and Example

What is phagocytosis? Phagocytosis is a process by which cells ingest large particles (> 0.5 micrometers) into membrane-bound vesicles called phagosomes, which are then targeted to the lysosomes for enzymatic … Read more

Dendritic Cells- Definition, Structure, Immunity, Types, Functions

September 17, 2022April 30, 2022 by Anupama Sapkota
Dendritic Cells

Dendritic cells are key antigen-presenting cells of the immune system that inform other effector immune cells to fight against invasive pathogens. These are also called professional antigen-presenting cells as these … Read more

Vaccines- Definition, Principle, Types, Examples, Side Effects

November 19, 2023April 29, 2022 by Faith Mokobi
Vaccines- Introduction and Types

A vaccine is a medical preparation given to provide immunity from a disease. Vaccines use a variety of different substances ranging from dead microorganisms to genetically engineered antigens to defend … Read more

Natural Killer (NK) Cells- Definition, Structure, Immunity, Functions

September 25, 2022April 28, 2022 by Anupama Sapkota
Natural Killer (NK) Cells

What are Natural Killer (NK) Cells? Definition of NK Cells Natural killer (NK) cells are a group of innate lymphocyte cells with cytolytic activity against virus-infected cells and physiologically stressed … Read more

Active Immunity vs Passive Immunity- 19 Key Differences

August 3, 2023April 20, 2022 by Sagar Aryal, PhD
Differences between Active Immunity and Passive Immunity

Immunity can be defined as the ability of a multicellular organism’s body to protect itself from foreign agents and infectious agents, by being able to destroy them to prevent further … Read more

Stem Cells- Definition, Properties, Types, Uses, Challenges

May 4, 2022April 12, 2022 by Anupama Sapkota
Stem Cells- Sources, Characteristics, Types, Uses

Stem Cells Definition Stem cells are unique cells present in the body that have the potential to differentiate into various cell types or divide indefinitely to produce other stem cells. … Read more

T Cell (T Lymphocyte)- Definition, Types, Development, Applications

July 11, 2022April 10, 2022 by Anupama Sapkota
T Cell (T Lymphocyte)- Definition, Types, Development, Applications

T Cell (T Lymphocyte) Definition Thymus-derived lymphocytes or T cells are cells of the immune system that are an essential part of the adaptive immune system. These are blood cells … Read more

5 Types of Immunoglobulins: IgG, IgM, IgA, IgD, and IgE

August 3, 2023April 4, 2022 by Anupama Sapkota
Antibody Types or Classes

Antibodies, also known as immunoglobulins, are proteins produced by lymphocytes as a result of interaction with antigens. Antibodies are a part of the humoral immune of the adaptive immune system … Read more

Blood Cells- Definition and Types with Structure and Functions

September 20, 2022March 29, 2022 by Anupama Sapkota
Blood Cells- Definition and Types with Structure and Functions

Blood cells, also known as hematocytes, hemocytes, or hematopoietic cells, are cells produced mostly in the blood and are synthesized primarily in the red bone marrow. Blood cells make up … Read more

Antigen vs Antibody- Definition and 12 Major Differences

September 20, 2022March 26, 2022 by Sagar Aryal, PhD
Differences between antigen and antibody

Differences between antigen and antibody Antibodies are produced by the immune system in response to antigens (material perceived as foreign). The antibody response to a particular antigen is highly specific … Read more

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