Factors affecting Immunogenicity

Factors affecting Immunogenicity

Immunogenicity is determined by: A. Properties of Immunogen Foreignness An antigen must be a foreign substance to the animal or recognized as non-self by the biological system to elicit an immune response. E.g. Bovine serum albumin, a common experiment antigen is not immunogenic when injected to the cow but strongly immunogenic when injected to the … Read more Factors affecting Immunogenicity

Introduction to Antigen

Introduction to Antigen

Antigens are specifically defined as molecules that interact specifically with immunoglobulin receptor of B-cell (or T-cell when complexed with MHC) or antigen is any substance that may be specifically bound by an antibody molecule or T cell receptor. Antigen is a substance which when introduced into living animal evokes specific immune response either by producing … Read more Introduction to Antigen