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Reeju Sharma

Reeju Sharma completed her Master’s degree (M.Sc.) in medical microbiology from St. Xavier's College, Tribhuvan University, Kathmandu, Nepal, and did her bachelor’s degree (B.Sc.) in general microbiology. She is currently working in a pharmaceutical company as a Quality control officer.

Cell Wall Synthesis Inhibitors: Examples, Inhibition, Resistance

July 28, 2024August 3, 2023 by Reeju Sharma
Cell wall synthesis inhibitors

Generally, the bacterial cell consists of a cell wall, cell membrane, and nucleoid.  The cell wall is the outer covering of the bacteria-containing peptidoglycan layer which is made up of … Read more

Microbial Production of Penicillin- Definition, Biosynthesis, Process, Uses

August 3, 2023 by Reeju Sharma
Microbial Production of Penicillin

What is Penicillin? Alexander Fleming in September 1928 accidentally discovered Penicillin. He found that the fungus, Penicillium notatum prevented the growth of bacteria, Staphylococcus spp.. Later Clutterbuck and his colleagues … Read more

Folic acid synthesis inhibitors- Definition, Examples, Inhibition, Resistance

August 3, 2023 by Reeju Sharma
Folic acid synthesis inhibitors

Folic acids are the enzymes that are necessary for bacterial protein synthesis and the synthesis of amino acids. Trimethoprim and Sulfonamides are the antimicrobial classes that interfere with the synthesis … Read more

Mycolic acid biosynthesis inhibitors- Definition, Examples, Inhibition, Resistance

August 3, 2023 by Reeju Sharma
Mycolic acid biosynthesis inhibitors

Mycolic acid is the cell wall that contains α-alkylated β-hydroxylated fatty acids present in Mycobacteria, Nocardia, and Corynebacteria. Mycolic acids are the main component of the cell wall of Mycobacterium … Read more

RNA Synthesis Inhibitors- Definition, Examples, Inhibition, Resistance

August 3, 2023 by Reeju Sharma
RNA Synthesis Inhibitors- Rifamycin

RNA stands for Ribonucleic acid is a polymer of ribonucleotides. Transcription is the process in which DNA is transcribed into RNA with the help of the enzyme RNA polymerase. Transcription … Read more

DNA Synthesis Inhibitors- Definition, Examples, Inhibition, Resistance

August 3, 2023 by Reeju Sharma
DNA Synthesis Inhibitors

What are DNA Synthesis Inhibitors? DNA synthesis occurs at chromosomes which requires substrates, primers, templates, and enzymes. Different drugs were used in treating diseases by inhibiting DNA synthesis in different … Read more

Cell Membrane Inhibitors: Examples, Inhibition, Resistance

August 3, 2023 by Reeju Sharma
Cell Membrane Inhibitors

In this era, bacterial membrane became the new target for the antimicrobial agent because anionic lipids are present in bacterial surfaces and the antimicrobials are cationic so they show greater … Read more

Protein Synthesis Inhibitors- Definition, Examples, Inhibition, Resistance

August 3, 2023 by Reeju Sharma
Protein synthesis inhibitors

What are Protein synthesis inhibitors? Protein synthesis, a long process that includes different enzymes and structural change in organisms. Some antibacterial classes inhibit bacterial protein synthesis by interfering with the … Read more

Kirby Bauer Disc Diffusion Method For Antibiotic Susceptibility Testing

May 17, 2023May 18, 2022 by Reeju Sharma
Kirby Bauer Disc Diffusion Method For Antibiotic Susceptibility Testing

As the Broth dilution method are time-consuming, many laboratories in the United States adopted disc diffusion tests in the early 1950s. Kirby Bauer tests also known as the Disc diffusion … Read more

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