||Red Blood Cells (RBCs)
||White Blood Cells (WBCs)
||In the embryonic phase, they are formed in the liver and spleen. However, after birth, they are formed in the red bone marrow.
||They are formed in red bone marrow, lymph nodes, spleen, etc
||Process of Formation
||Formation of RBCs is called “Erythropoiesis”
||Formation of WBCs is called “Leucopoiesis”
||More abundant (4-5 million /mm3) They are the most abundant cell in the blood, accounting for about 40 to 45 percent of its volume.
||They are much fewer in number than red blood cells, accounting for about 1 percent of blood (8000 /mm3).
||Smaller than WBC ( 0.008 mm diameter )
||Larger than RBC (0.02mm)
||Irregular or round in shape
||Red cells are pinkish‐brown in color.
||White cells are colorless.
||The complex protein, hemoglobin, is the major constituent of RBCs.
||Hemoglobin is absent in WBCs.
||The nucleus is absent (anucleate).
||Present and may be bilobed, irregular or round.
||Belong to the cardiovascular system
||Belong to the lymphatic system
||In healthy people, there are at least five types of white cells in the circulating blood. White cells are divided into granulocytes, monocytes, and lymphocytes.
||Number increases during exercise or when at high altitudes.
||The infection leads to an increase in the number of WBCs.
||The average life span of 120 days
||Life span ranges from 5-21 days.
||Non-motile but can move through circulation and have the ability to squeeze through small capillaries.
||Movement is Primarily between the cardiovascular system
||Between the cardiovascular and lymphatic systems.
||Do not leave the blood vessel
||They can leave blood from capillaries and land in tissues.
||Forms stacks or aggregation called Rouleaux
||Do not form Rouleaux
||Disorders result in anemia, thalassemia, polycythemia vera, etc.
||Lymphoma, Leukemia, Myelodysplastic syndrome (MDS)
||Carry respiratory gases- oxygen and carbon dioxide. Also, it contributes to blood viscosity.
||Phagocytosis and defensive role including antibody production.