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Instrumentation

Instrumentation is a collection of devices and mechanics used to measure, evaluate, and test systems.

  • In biology, the instrumentation is considered a part of biomedical engineering where the working mechanism and the parts of a system are studies.
  • Instrumentation in biology or Bioinstrumentation is primarily concentrated on bringing the engineering and medical worlds together.
  • Different devices like centrifuges and autoclaves that are common in biological laboratories are a part of the instrumentation. Studies done in instrumentations allow the understanding of the parts and working mechanisms of such devices.
  • Other important techniques include chromatography which is routinely performed in laboratories to separate biological systems, which are also equally important.
  • Instrumentation is still an emerging discipline with new pieces of machinery still being produced for convenience in laboratories.
  • The application of bio-instruments is not only limited to laboratories as modern agriculture makes use of bio-instruments to monitor and evaluate soil and to measure plant growth.
  • Besides, these instruments can also be used to determine the physiological activities of plants like the carbon dioxide trade rate, net photosynthesis, etc.
  • Processes like electrophoresis make use of nucleic acids along with biosensors to compare the DNA sequences. This enables genetic testing and diagnosis of various diseases.
  • Genetic testing is heavily influenced by the progress made in instrumentation as new devices and techniques are discovered which makes the process faster, more accurate, and more reliable.
  • As RT-PCR and blotting are considered advanced molecular diagnosis methods, disease diagnosis becomes faster and more accurate than ever. 
  • Determination of radioisotopes and concentration of a solution has been made easier with techniques like spectroscopy and colorimetry.
  • As the discipline continues to grow, the main focus of the field remains in the improvements of technology to make the medical processes faster and more efficient.
  • Instrumentation, thus, is slowly becoming an integral part of all biological fields with new emerging new technology and the discovery of fast and reliable procedures.

Gel Filtration Chromatography- Definition, Principle, Types, Parts, Steps, Uses

March 1, 2022January 26, 2022 by Sagar Aryal, PhD
Gel Filtration Chromatography

Biomolecules are purified using different techniques that separate them according to the differences in their specific properties such as size, hydrophobicity, biorecognition, charge, etc. Gel filtration is a technique in … Read more

X-Ray Spectroscopy- Definition, Principle, Steps, Parts, Uses

March 1, 2022January 22, 2022 by Sagar Aryal, PhD
X-Ray Spectroscopy

X-rays make up X-radiation, a form of electromagnetic radiation. Most X-rays have a wavelength ranging from 0.01 to 10 nanometers, corresponding to frequencies in the range 30 petahertz to 30 exahertz (3×1016 Hz to 3×1019 Hz) and energies in the range 100 eV to 100 keV, produced … Read more

UV Spectroscopy- Definition, Principle, Steps, Parts, Uses

April 21, 2022January 21, 2022 by Sagar Aryal, PhD
UV Spectroscopy

What is UV Spectroscopy? Spectroscopy is the measurement and interpretation of electromagnetic radiation absorbed or emitted when the molecules or atoms or ions of a sample move from one energy … Read more

Gamma-ray Spectroscopy- Definition, Principle, Parts, Uses

March 1, 2022January 20, 2022 by Sagar Aryal, PhD
gamma-ray spectrometer

Gamma rays are an ultrahigh-frequency of light that is emitted by radioactive elements, energetic celestial bodies such as black holes and neutron stars, and high energy events such as nuclear … Read more

Paper Chromatography- Definition, Types, Principle, Steps, Uses

April 21, 2022January 19, 2022 by Sagar Aryal, PhD
Paper Chromatography

What is Paper Chromatography? Paper chromatography (PC) is a type of planar chromatography whereby chromatography procedures are run on a specialized paper. PC is considered to be the simplest and … Read more

Beer-Lambert Law- Definition, Derivation, and Limitations

March 1, 2022January 13, 2022 by Sagar Aryal, PhD
Beer-Lambert Law

The Beer-Lambert law, also known as Beer’s law, the Lambert-Beer law, or the Beer-Lambert–Bouguer law relates the attenuation of light to the properties of the material through which the light is traveling. What is Beer-Lambert Law? When a monochromatic … Read more

NMR Spectroscopy- Definition, Principle, Steps, Parts, Uses

August 3, 2023January 12, 2022 by Sagar Aryal, PhD
Nuclear Magnetic Resonance (NMR) Spectroscopy

What is NMR? Nuclear magnetic resonance spectroscopy, most commonly known as NMR spectroscopy or magnetic resonance spectroscopy (MRS), is a spectroscopic technique to observe local magnetic fields around atomic nuclei.  It is a spectroscopy technique that … Read more

Infrared (IR) Spectroscopy- Definition, Principle, Parts, Uses

March 1, 2022January 8, 2022 by Sagar Aryal, PhD
Infrared (IR) Spectroscopy

What is Infrared (IR) Spectroscopy? Infrared (IR) spectroscopy or vibrational spectroscopy is an analytical technique that takes advantage of the vibrational transitions of a molecule. It is one of the … Read more

Cell Disruption- Definition, Methods, Types, Significance

July 9, 2024October 10, 2021 by Sagar Aryal, PhD
Cell Disruption Methods

Mechanical Methods of Cell Disruption Mechanical methods are those methods that required some sort of force to separate out intracellular protein without adding chemical or enzyme Mortar & Pestle Blenders … Read more

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