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Instrumentation

Instrumentation is a collection of devices and mechanics used to measure, evaluate, and test systems.

  • In biology, the instrumentation is considered a part of biomedical engineering where the working mechanism and the parts of a system are studies.
  • Instrumentation in biology or Bioinstrumentation is primarily concentrated on bringing the engineering and medical worlds together.
  • Different devices like centrifuges and autoclaves that are common in biological laboratories are a part of the instrumentation. Studies done in instrumentations allow the understanding of the parts and working mechanisms of such devices.
  • Other important techniques include chromatography which is routinely performed in laboratories to separate biological systems, which are also equally important.
  • Instrumentation is still an emerging discipline with new pieces of machinery still being produced for convenience in laboratories.
  • The application of bio-instruments is not only limited to laboratories as modern agriculture makes use of bio-instruments to monitor and evaluate soil and to measure plant growth.
  • Besides, these instruments can also be used to determine the physiological activities of plants like the carbon dioxide trade rate, net photosynthesis, etc.
  • Processes like electrophoresis make use of nucleic acids along with biosensors to compare the DNA sequences. This enables genetic testing and diagnosis of various diseases.
  • Genetic testing is heavily influenced by the progress made in instrumentation as new devices and techniques are discovered which makes the process faster, more accurate, and more reliable.
  • As RT-PCR and blotting are considered advanced molecular diagnosis methods, disease diagnosis becomes faster and more accurate than ever. 
  • Determination of radioisotopes and concentration of a solution has been made easier with techniques like spectroscopy and colorimetry.
  • As the discipline continues to grow, the main focus of the field remains in the improvements of technology to make the medical processes faster and more efficient.
  • Instrumentation, thus, is slowly becoming an integral part of all biological fields with new emerging new technology and the discovery of fast and reliable procedures.

Gas Chromatography: Principle, Parts, Steps, Procedure, Uses

March 13, 2026March 8, 2026 by Sanju Tamang
Principle of Gas Chromatography

Gas chromatography (GC) is a type of chromatography used to separate and analyze volatile compounds. This separation occurs in an instrument called gas chromatograph that uses an inert gas as … Read more

Flash Chromatography: Principle, Parts, Steps, Examples, Uses

March 13, 2026March 7, 2026 by Sanju Tamang
Flash Chromatography

Flash chromatography is a method used for the rapid separation and purification of chemical compounds in a mixture. It is also known as flash column chromatography or medium-pressure liquid chromatography. … Read more

Fast Protein Liquid Chromatography (FPLC): Principle, Steps, Uses

March 11, 2026March 6, 2026 by Sanju Tamang
Fast Protein Liquid Chromatography (FPLC)

Fast Protein Liquid Chromatography (FPLC) is a liquid chromatography technique used for the separation and purification of proteins and other biomolecules. It was developed in the 1980s by Pharmacia and … Read more

Dye Ligand Chromatography: Principle, Components, Steps, Uses

March 10, 2026March 5, 2026 by Sanju Tamang
Dye Ligand Chromatography

Dye ligand chromatography is a type of affinity chromatography that uses synthetic dyes as ligands to purify target biomolecules, such as proteins and enzymes, from complex mixtures.  Unlike traditional affinity … Read more

Column Chromatography: Principle, Parts, Types, Steps, Uses

March 1, 2026 by Sanju Tamang
Column Chromatography

Column chromatography is a method that separates and purifies the components of a mixture on a vertical column or tube based on their interactions with the stationary and mobile phases. … Read more

Countercurrent Chromatography: Principle, Parts, Types, Steps, Uses

March 1, 2026February 25, 2026 by Sanju Tamang
Countercurrent Chromatography

Countercurrent chromatography (CCC) is a liquid chromatography (LC) method that separates chemical compounds in a mixture based on their differential solubility between two immiscible liquid phases in a solid-support-free system. … Read more

PCR Machine: Principle, Parts, Steps, Types, Uses, Examples

August 8, 2025July 12, 2025 by Prakriti Karki
PCR Machine

PCR machine is also known as thermal cyclers or DNA amplifiers, or thermocyclers. PCR machines amplify small segments of DNA or RNA chosen from the genome with a primer. It … Read more

Chromatography: Principle, Types, Steps, Uses, Diagram

June 14, 2025June 8, 2025 by Sanju Tamang
Chromatography

Chromatography is a method used to separate the individual components of a mixture on the basis of their interactions with a stationary and a mobile phase. Each component interacts differently … Read more

14 Types of Chromatography (Definition, Principle, Steps, Uses)

June 14, 2025June 7, 2025 by Anupama Sapkota
Types of Chromatography (Definition, Principle, Steps, Uses)

Chromatography Definition Chromatography is an important biophysical technique that enables the separation, identification, and purification of the components of a mixture for qualitative and quantitative analysis. What is a stationary … Read more

Affinity Chromatography: Principle, Parts, Steps, Uses

April 3, 2025March 31, 2025 by Anjali Rawal
Affinity Chromatography

Chromatography is a widely used laboratory technique for the separation of components in a mixture based on their differential interactions with the stationary phase.  This technique aids in the identification … Read more

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