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Basic Microbiology

Microbiology is the branch of science that deals with microscopic organisms and their interaction with other microscopic and macroscopic organisms.

  • Microorganisms are tiny microscopic organisms that are too small to be seen with naked eyes and thus, can only be seen with a microscope. Microorganisms include microscopic organisms like bacteria, fungi, archaea, protozoa, and viruses.
  • Basic microscopy deals with a diverse group of studies that help in research related to the biochemistry, physiology, cell biology, ecology, evolution, and clinical aspects of microorganisms, including the host response to these agents.
  • Microbiology also deals with the structure, function, classification of such organisms, along with exploiting and controlling their activities.
  • The concept of microbiology began with the discovery of the microscope by Anton Von Leeuwenhoek.
  • On the one hand, microbes are used for their unique features which allow the production of antibiotics, amino acids, hormones, and other therapeutic compounds, and also the production of food and food-related products.
  • Microorganisms are also involved in the decomposition of components such as lignocellulosic biomass for second-generation ethanol or biogas.
  • Similarly, certain genetic features and biochemical abilities of microorganisms make them dangerous for industry (food spoilage) as well as human health.
  • Microbiology, initially, was only associated with pathogenic microorganisms that result in different forms of diseases in different groups of living beings.
  • With the establishment of microbiology as a discipline, the application of microorganisms in different areas has also increased.
  • The use of microorganisms in food and pharmaceuticals has given rise to the branching of microbiology into further disciplines and studies.
  • Thus, over the years, the branch has been classified into further groups like agriculture microbiology, food microbiology, pharmaceutical microbiology, systemic microbiology, etc.
  • The studies in microbiology have also increased due to the use of microorganisms in different researches as these are easy to manipulate and reproduce when compared to other living organisms.
  • Studies in microbiology are essential for the discovery of new and advanced methods for the discovery of emerging microorganisms and associated diseases and applications.
  • Microbiology also deals with techniques for the identification of these microorganisms, their classification, and the life cycle.
  • All of this allows for a better understanding of microorganisms and their role in maintaining the ecosystem.
  • Microbiology and microorganisms can be applied for the formation of new genetically engineered microorganisms by a process like genetic recombination.
  • Besides, different microorganisms have found their application in the production of food, industrial products, and antibiotics.

Physical methods of sterilization- Heat, Filtration, Radiation

July 27, 2021May 11, 2021 by Anupama Sapkota
Physical methods of sterilization- Heat, Filtration, Radiation

What is Sterilization? Sterilization is the complete removal of microorganisms from an object or surfaces. Sterilization is obtained when microorganisms are subjected to antimicrobial agents for sufficient time and at … Read more

McFarland Standards- Principle, Preparation, Uses, Limitations

April 21, 2022May 5, 2021 by Sagar Aryal
McFarland Standards- Principle, Preparation, Uses, Limitations

What is McFarland Standards? McFarland Standards are used as the reference in order to adjust the turbidity of the liquid/ bacterial suspension in the vial or tube in the microbiology … Read more

What is Sensitivity, Specificity, False positive, False negative?

April 21, 2022April 18, 2021 by Faith Mokobi
What is Sensitivity, Specificity, False positive, False negative

These are terms that are fundamental to understanding the utility of clinical tests. They are the most essential variables when designing diagnostic tests, in determining how reliable the tests are … Read more

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