Bacterial vaginosis

Pathogenesis and Clinical manifestation of Gardenerella vaginalis

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Pathogenesis and Clinical manifestation of Gardenerella vaginalis

Pathogenesis of Gardenerella vaginalis A. Adherence of G. vaginalis to Host Epithelium: Initial Steps in Invasion The initial steps of establishing infection include adherence to host receptor sites, production of cytotoxic substances specific for host cells, and biofilm formation. vaginais  produces  vaginolysin, a cholesterol-dependent cytolysin, for human cells and encodes a pore-forming toxin that binds … Read more Pathogenesis and Clinical manifestation of Gardenerella vaginalis

Laboratory diagnosis of Bacterial vaginosis caused by Gardnerella vaginalis

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Laboratory diagnosis of Bacterial vaginosis caused by Gardnerella vaginalis Specimen: Vaginal discharge specimen A. Direct Microscopic Examination Bacterial Vaginosis (BV) is characterized by a foul-smelling discharge. A diagnosis/confirmation is done microscopically by examination of gram stains to detect change in vaginal ecology. A smear of vaginal fluid or vaginal swab is gram stained which reveals … Read more Laboratory diagnosis of Bacterial vaginosis caused by Gardnerella vaginalis