Bacterial vaginosis Archives

Pathogenesis and Clinical manifestation of Gardenerella vaginalis

February 4, 2021October 22, 2017 by Sagar Aryal

Pathogenesis of Gardenerella vaginalis A. Adherence of G. vaginalis to Host Epithelium: Initial Steps in Invasion The initial steps of establishing infection include adherence to host receptor sites, production of cytotoxic substances specific for host cells, and biofilm formation. vaginais produces vaginolysin, a cholesterol-dependent cytolysin, for human cells and encodes a pore-forming toxin that binds to the CD59 human complement …

Laboratory diagnosis of Bacterial vaginosis caused by Gardnerella vaginalis

February 4, 2021October 20, 2017 by Sagar Aryal

Laboratory diagnosis of Bacterial vaginosis caused by Gardnerella vaginalis Specimen: Vaginal discharge specimen A. Direct Microscopic Examination Bacterial Vaginosis (BV) is characterized by a foul-smelling discharge. A diagnosis/confirmation is done microscopically by examination of gram stains to detect change in vaginal ecology. A smear of vaginal fluid or vaginal swab is gram stained which reveals the presence of Gram negative …