Pathogenesis and Clinical manifestation of Gardenerella vaginalis
Pathogenesis of Gardenerella vaginalis A. Adherence of G. vaginalis to Host Epithelium: Initial Steps in Invasion The initial steps of establishing infection include adherence to host receptor sites, production of cytotoxic substances specific for host cells, and biofilm formation. vaginais produces vaginolysin, a cholesterol-dependent cytolysin, for human cells and encodes a pore-forming toxin that binds to the CD59 human complement …
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