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Genetics

Genetics is a branch of natural science that deals with heredity due to the transmission of genes, gene regulation, and gene manipulation.

  • Genetics is a connecting link between many disciplines like microbiology, biotechnology, medicine, and agriculture.
  • Studies involving genes and chromosomes of living beings began quite late as it requires significant advances in the microscopy area.
  • The influence of heredity and its application of cultivation and production improved organisms, however, had been recognized since ancient times.
  • The study of genes and genetics began as a major concept after studies made by Mendel on pea plants. It was further strengthened and flourished by the works of Morgan.
  • Eventually, genetics became a distinct area of study with the identification of genes and the study of genes at different levels, including their role in the cell, their regulation, and their expression.
  • Initially, genetics was limited to understanding the concept and process of heredity via techniques like the formation of Punnet’s square. With the development of techniques like X-ray diffraction, the structure of DNA, and the presence of genetic code were established. This paved the way for modern genetics.
  • Modern genetics focuses on the chemical composition of structures found in genes like the DNA that influences the chemical reactions taking place in the cell.
  • Gene expression is influenced by two major factors; the genetic composition and the influence of the environment.
  • The influence of the environment on gene expression can be distinctly observed in green plants where the gene responsible for the formation of chlorophyll is only expressed in the presence of sunlight.
  •  Genes, through the proteins they encode, determine how efficiently foods and chemicals are metabolized, how effectively toxins are detoxified, and even how vigorously infections are targeted.
  • Processes like mutations are now a significant cause of major genetic diseases. The mutations might arise due to a complex combination of genetic, behavioral, and environmental factors.

Mutation: Causes, Mechanisms, Agents and Significance

September 9, 2023August 3, 2023 by Sagar Aryal, PhD
Mutation- Causes, Mechanisms, Agents and Significance

Causes and Mechanisms of Mutation Agents of Mutations Radiation and Radioactive Decays Temperature Chemical Agents Biological agents Significance of Mutations References

What are the types of Mutations?

September 9, 2023August 3, 2023 by Sagar Aryal, PhD
Types of Mutations

The mutation is a process that produces a gene or chromosome that differs from the wild type (arbitrary standard for what “normal” is for an organism). The mutation may result … Read more

Mendel’s 3 Laws (Segregation, Independent Assortment, Dominance)

August 3, 2023 by Sagar Aryal, PhD
Mendel's Laws

Mendel’s Experiment Mendel carried out breeding experiments in his monastery’s garden to test inheritance patterns. He selectively cross-bred common pea plants (Pisum sativum) with selected traits over several generations.  After crossing … Read more

Somatic Mutation vs. Germline Mutation: 13 Key Differences

August 3, 2023 by Prashant Dahal
Somatic Mutation vs. Germline Mutation

A mutation is defined as the sudden change in gene i.e. nucleotide sequences in DNA, which may be qualitative or quantitative change. This may or may not be inheritable. Mutations … Read more

Test Cross (Single, Two, Triple Gene)- Definition, Examples, Uses

August 3, 2023 by Prashant Dahal
Test Cross Types and Examples

Phenotypic characters can be easily separated just by looking at the individual. It’s not that easy to determine the genotypic character of that same individual. This is because, genetically a … Read more

Chromosomes- Definition, Structure, Types, Model, Functions

August 3, 2023 by Sagar Aryal, PhD
Chromosomes Definition Structure Types Model Functions

What are Chromosomes? In the nucleus of each cell, the DNA molecule is packaged into thread-like structures called chromosomes. Each chromosome is made up of DNA tightly coiled many times … Read more

Artificial Selection- Definition, Steps, Examples, Uses

August 3, 2023 by Aiman Fatima
Artificial Selection or Selective Breeding

Artificial Selection is also known as Selective Breeding. Charles Darwin introduced the term Artificial Selection in his book ‘On the Origin of Species (1859). Darwin Artificial selection happened at HMS … Read more

Mendel’s Law of Dominance- Definition, Examples, Limitations

August 3, 2023 by Anupama Sapkota
Mendel’s Law of Dominance

Mendel’s Law of Dominance Definition Mendel’s Law of Dominance states that ‘In crossing between homozygous organisms for contrasting characters of a pair, only one character of the pair appears in … Read more

Mendel’s Law of Segregation- Definition, Examples, Limitations

August 3, 2023 by Anupama Sapkota
Mendel's Law of Segregation

Mendel’s Law of Segregation Definition Mendel’s Law of Segregation states that ‘The hybrids or heterozygotes of F1 generation have two contrasting characters of dominant and recessive nature where the alleles … Read more

Punnett Square- Definition, Types, Application, Examples, Limitations

August 3, 2023 by Anupama Sapkota
Punnett Square in Pea Plant

Punnett Square Definition The Punnett square is a table or checkboard grid that is used to determine all possible genotypes from a particular cross. Punnett square is a simple square … Read more

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