Sanju Tamang

Helicos single-molecule sequencing, also called true single-molecule sequencing (tSMS), is a third-generation DNA sequencing technology that directly reads individual DNA or RNA molecules without requiring complex steps like PCR amplification. … Read more

Polony sequencing is an open-source DNA sequencing technology that involves clonal amplification of DNA fragments into polymerase colonies called polonies. It was developed by Dr. George Church and his team … Read more

Targeted sequencing is a method that sequences specific genomic regions of interest rather than sequencing the whole genome. By focusing on particular genes or regions, targeted sequencing offers a more … Read more

Mate-pair sequencing is a next-generation sequencing method that creates long-insert paired-end DNA libraries. In this sequencing method, two DNA fragments that are far apart in the genome and have opposite … Read more

Illumina sequencing is one of the most widely used next-generation sequencing (NGS) technology that uses sequencing by synthesis to detect individual DNA bases as they are added to a growing … Read more

SOLiD (Sequencing by Oligonucleotide Ligation and Detection) is a second-generation sequencing platform that uses sequencing by ligation method to determine the sequence of nucleotides in target DNA. It was developed … Read more

Ion Torrent Sequencing is a next-generation sequencing method that uses a semiconductor chip to directly detect the hydrogen ions (H+) released during DNA synthesis. Ion Torrent technology introduced the first … Read more

Methylation sequencing is a method of sequencing used to study DNA methylation patterns across the genome which is an important biological process that adds methyl group (CH3) to the cytosine … Read more