Virulence factors of Listeria monocytogenes 1. Adhesion proteins (Ami, Fbp A, flagellin) Mediate bacterial binding to host cell that contribute to virulence. 2. Listeriolysin O A hemolytic and cytotoxic toxin that allows for survival within phagocytes. 3. Internalin Cell surface protein … Read more
Virulence factors of Streptococcus pyogenes A. Antigenic structure M protein: rod like coiled structure with two major structural classes; Class I and Class II ;major virulence factor;resist phagocytosis and intracellular killing by polymorphonuclear leukocytes in the absence of antibodies. B. … Read more
Virulence factors or antigenic structures of Neisseria gonorrhoeae A. Pili Pili are the hair like appendages that extend up to several micrometers from the gonococcal surface. It mediates the exchange of genetic material between strains and attachment to human mucosal … Read more
Virulence factors of Streptococcus pneumoniae Polysaccharide capsule The capsule is antiphagocytic, inhibiting complement deposition and phagocytosis. 2. Cell wall associated polymers and proteins Teichoic acid – binds to epithelial cells and activates alternative complement pathway Protein adhesion – binds to … Read more
Virulence factors of Legionella pneumophila Heat shock protein 60: enhances invasion and cytokine expression in macrophages. Outer membrane protein: binding with and delivery of packaged materials into the eukaryotic cells. inhibit the fusion of phagosomes with lysosomes. Macrophage infectivity potentiator (Mip) … Read more