Pathogenesis and Clinical Manifestations of Mycobacterium leprae

Pathogenesis and Clinical Manifestations of Mycobacterium leprae

Pathogenesis of Mycobacterium leprae M. leprae is an acid-fast, gram-positive obligate intracellular bacillus that shows tropism for cells of the reticuloendothelial system and peripheral nervous system (notably Schwann cells). Organisms may be acquired by the susceptible host usually through respiratory system or by way of skin to skin contact (between exudates of a leprosy patient’s skin lesions and the abraded skin …

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