Chromosomal Mutation- Definition, Causes, Mechanism, Types, Examples

Chromosomal Mutations

What are Chromosomes? Chromosomes are long thread-like structures of DNA that contain part or all of the genetic material of an organism. Chromosomes exist in a complex three-dimensional structure which is essential in transcriptional regulation. Chromosomes exhibit unique compactness as the unraveled form of the chromosome would be metered in length, but the compact form can be easily placed within …

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Frameshift Mutation- Definition, Causes, Mechanism, Applications, Examples

Frameshift Mutation

Frameshift mutation definition A frameshift mutation is a type of genetic mutation resulting from the alteration of a number of nucleotides in DNA sequences that are not multiple of three. Frameshift mutation occurs as a result of a change in the reading frame of the sequence. Since the codons for gene expression occur in the form of triplets, the difference …

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Silent Mutation- Definition, Causes, Mechanism, Applications, Examples

Silent Mutation

What are Silent mutations? Silent mutations are mutations where the changes in the nucleotide sequence of DNA do not produce any observable effect on the organism. The change in nucleotide doesn’t produce a change in the amino acid sequence or the structure and function of the protein. Silent mutations are also termed neutral mutations as these do not cause any …

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Nonsense Mutation- Definition, Causes, Mechanism, Applications, Examples

Nonsense Mutation

Nonsense mutation definition A nonsense mutation is a type of mutation where a premature stop codon is added to a sequence which hinders the further translation of the protein-coding gene. The nonsense mutation is classified as a loss-of-function change where the mutation impairs the production of a particular protein. Nonsense mutation, like most other mutations, can have a range of …

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Missense Mutation- Definition, Causes, Mechanism, Types, Examples

Missense-Mutation

Missense mutation definition A missense mutation is a type of mutation where the alteration of a nucleotide base in a gene sequence results in the translation of different amino acids in the protein. A missense mutation is a type of nonsynonymous substitution in a DNA sequence, indicating that the mutation results in some kind of effect on the resulting sequence. …

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Point mutation- Definition, Causes, Mechanism, Types, Examples, Applications

Point mutation

Point mutation definition Point mutation is a type of genetic mutation where one of the base pairs in the DNA sequence is altered either by insertion or deletion. Point mutation, as the name indicates, occurs at a particular point of the DNA sequence as a result of changes in one particular base pair. Usually, point mutations arise as a result …

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Mutation- Causes, Mechanisms, Agents and Significance

Mutation- Causes, Mechanisms, Agents and Significance

Mutation is a process that produces a gene or chromosome that differs from the wild type (arbitrary standard for what “normal” is for an organism). It is most commonly defined as a spontaneous permanent change in a gene or chromosome which usually produces a detectable effect in the organism concerned and is transmitted to the offsprings. Mutated gene or chromosome …

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