DNA Methylation

DNA methylation is a process by which methyl groups are added to the DNA molecule. It is an epigenetic mechanism that occurs by the addition of a methyl (-CH3) group to DNA, thereby often modifying the function of the genes and affecting gene expression.  The most widely characterized DNA methylation process is the covalent addition of the methyl group at the 5-carbon of the cytosine ring resulting in …

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Post Translational Modification

Post Translational Modification

Post Translational Modification Post translational modifications refer to any alteration in the amino acid sequence of the protein after its synthesis. It may involve the modification of the amino acid side chain, terminal amino or carboxyl group by means of covalent or enzymatic means following protein biosynthesis. Generally, these modifications influence the structure, stability, activity, cellular localization or substrate specificity of the …

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