Acinetobacter baumannii- Pathogenicity and Clinical Features

Acinetobacter baumannii- Pathogenicity and Clinical Features

Acinetobacter baumannii- Pathogenicity and Clinical Features Acinetobacters are strictly aerobic, oxidase-negative, plump gram-negative coccobacilli which are ubiquitous saprophytes, recovered in nature and in the hospitals. They are opportunistic pathogens that cause infections in the respiratory tract, urinary tract, and wounds; they also cause septicemia. Acinetobacter is subdivided into two groups: glucose oxidizing species ( A. … Read moreAcinetobacter baumannii- Pathogenicity and Clinical Features

Herpes simplex virus 1 (HSV-1)

Herpes simplex virus 1 (HSV-1)

Herpes simplex virus 1 (HSV-1) Structure of Herpes simplex virus 1 (HSV-1) Herpesviruses are large (150-200 nm size), spherical in shape with icosahedral symmetry. The icosahedral protein capsid with average diameter 100 nm consists of 162 hollow hexagonal and pentagonal capsomeres with an electron-dense core containing the double stranded DNA genome with 125-240 kbp nucleotides … Read moreHerpes simplex virus 1 (HSV-1)

Differences between Meningitis and Encephalitis

Differences between Meningitis and Encephalitis

Differences between Meningitis and Encephalitis Meningitis and Encephalitis are the two main kinds of neurological conditions related to the brain and spinal cord, where the layer surrounding the brain or the brain itself gets inflamed. S.N. Character Meningitis Encephalitis 1.       Definition Inflammation of the thin membranes that surround the brain and spinal cord called the meninges (mostly … Read moreDifferences between Meningitis and Encephalitis

Virulence factors, Pathogenesis and Clinical manifestations of Streptococcus pneumoniae

Virulence factors, Pathogenesis and Clinical manifestations of Streptococcus pneumoniae

Virulence factors of Streptococcus pneumoniae Polysaccharide capsule The capsule is antiphagocytic, inhibiting complement deposition and phagocytosis. 2. Cell wall associated polymers and proteins Teichoic acid – binds to epithelial cells and activates alternative complement pathway Protein adhesion – binds to epithelial cells Peptidogylcan – activates alternative complement pathway Phosphorylcholine – mediates invasion of host cell … Read moreVirulence factors, Pathogenesis and Clinical manifestations of Streptococcus pneumoniae