Major Histocompatibility Complex II- Structure, Mechanism and Functions

Major Histocompatibility Complex II- Structure, Mechanism and Functions

Major Histocompatibility Complex (MHC) is a part of the genome of all vertebrates that code for molecules which are important in immune recognition. In humans, the MHC is a cluster of genes located on chromosome 6 which code for MHC proteins also called Human Leukocyte Antigen (HLA). MHC proteins are a set of cell surface proteins essential … Read moreMajor Histocompatibility Complex II- Structure, Mechanism and Functions

Major Histocompatibility Complex I- Structure, Mechanism and Functions

Major Histocompatibility Complex I- Structure, Mechanism and Functions

Major Histocompatibility Complex (MHC) is a part of the genome of all vertebrates that code for molecules which are important in immune recognition. In humans, the MHC is a cluster of genes located on chromosome 6 which code for MHC proteins also called Human Leukocyte Antigen (HLA). MHC proteins are a set of cell surface proteins essential … Read moreMajor Histocompatibility Complex I- Structure, Mechanism and Functions

Structure of Major Histocompatibility Complex (MHC)

Structure of Major Histocompatibility Complex (MHC)

Class I and Class II MHC antigens have a somewhat different structure. MHC Class I molecules MHC Class I molecules in both human and mouse consist of two polypeptide chains that dramatically differ in size. The larger (α) chain has a molecular weight of 44 kDa in humans and 47 kDa in the mouse, and … Read moreStructure of Major Histocompatibility Complex (MHC)

Major Histocompatibility Complex (MHC)- Types and Importance

Major Histocompatibility Complex (MHC)- Types and Importance

Major Histocompatibility Complex (MHC) Both T and B cells use surface molecules to recognize antigen, they accomplish this in very different ways. In contrast to antibodies or B-cell receptors, which can recognize an antigen alone, T-cell receptors only recognize pieces of antigen that are positioned on the surface of other cells. These antigen pieces are … Read moreMajor Histocompatibility Complex (MHC)- Types and Importance