Type 1 (Anaphylactic) Hypersensitivity Reaction

Type 1 (Anaphylactic) Hypersensitivity Reaction

Hypersensitivity is increased reactivity or increased sensitivity by the animal body to an antigen to which it has been previously exposed. The most widely adopted current classification is that of Coombs and Gellthat designates immunoglobulin-mediated (immediate) hypersensitivity reactions as types I, II, and III, and lymphoid cell-mediated (delayed-type) hypersensitivity/cell-mediated immunity as a type IV reaction. A hypersensitive response (HR) is …

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Autoimmune Disease

Autoimmune Disease

Autoimmune disease They occur when a specific adaptive immune response is mounted against self antigens. The normal consequence of an adaptive immune response against a foreign antigen is the clearance of the antigen from the body. Virus-infected cells, for example, are destroyed by cytotoxic T cells, whereas soluble antigens are cleared by formation of immune complexes of antibody and antigen, …

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