Hepatitis E Virus- An Overview

Hepatitis E Virus

Structure of Hepatitis E Virus Image: Schematic illustration of non-enveloped and quasi-enveloped HEV particles as well as enveloped virus. The putative model of quasi-enveloped HEV virion includes ORF3 product in its envelope as the existence of pORF3 has been confirmed by capturing quasi-enveloped HEV virion with anti-pORF3 antibodies and further supported by prediction of a putative transmembrane region in the N-terminal …

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Structure and Genome of Hepatitis E Virus

Structure of Hepatitis E Virus

Hepatitis E virus, discovered in 1983 by immune electron microscopy and first cloned in 1990. Structure of Hepatitis E Virus HEV is classified in the Calciviridae family because of its structural similarity to other calciviruses; however, it is now the sole member of the Hepeviridae family. The virus is non enveloped (naked) with icosahedral symmetry measuring 27-30 nm diameter. The genome is …

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Hepatitis A Virus- An Overview

Clinical Manifestations of Hepatitis A Virus

Structure of Hepatitis A Virus HAV (Hepatitis A Virus) is a distinct member of the picornavirus family, assigned to genus hepatovirus. HAV is a 27 nm to 32 nm spherical particle with icosahedral symmetry containing a linear single-stranded RNA genome with a size of 7.5 kb and non-enveloped. Hepatitis A virions have a primary buoyant density of 1.32 to 1.34 g/cc …

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Hepatitis C virus- An Overview

Hepatitis C virus

Structure of Hepatitis C virus Hepatitis C virus (HCV) is a RNA virus belonging to the family Flaviviridae, genus Hepacivirus. The HCV virion is 55-65 nm in diameter containing in it a 9.6 kb positive sense single-stranded RNA genome composed of a long open reading frame (ORF) flanked by untranslated regions (UTR’s) at both the ends. The genome of HCV is …

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