Mutation- Causes, Mechanisms, Agents and Significance

Mutation- Causes, Mechanisms, Agents and Significance

Mutation is a process that produces a gene or chromosome that differs from the wild type (arbitrary standard for what “normal” is for an organism). It is most commonly defined as a spontaneous permanent change in a gene or chromosome which usually produces a detectable effect in the organism concerned and is transmitted to the offsprings. Mutated gene or chromosome results from a mutational process while the organism or cell whose changed phenotype is attributed to a mutation is said … Read more

Frameshift Mutation- Definition, Causes, Mechanism, Applications, Examples

Frameshift Mutation

Frameshift mutation definition A frameshift mutation is a type of genetic mutation resulting from the alteration of a number of nucleotides in DNA sequences that are not multiple of three. Frameshift mutation occurs as a result of a change in the reading frame of the sequence. Since the codons for gene expression occur in the form of triplets, the difference in nucleotides results in the change in the frame. As a result of the change in the reading frame, a … Read more

Types of Mutations

Types of Mutations

The mutation is a process that produces a gene or chromosome that differs from the wild type (arbitrary standard for what “normal” is for an organism). The mutation may result due to changes either on the gene or the chromosome itself. Thus, broadly mutation maybe: Gene mutation where the allele of a gene changes. Chromosome mutation where segments of chromosomes, whole chromosomes, or entire sets of chromosomes change. Types of Mutations There are various schemes for classification of different kind … Read more