Pathogenesis and Clinical Manifestations of Borrelia burgdorferi

Pathogenesis and Clinical Manifestations of Borrelia burgdorferi

Pathogenesis of Lyme disease caused by Borrelia burgdorferi Lyme disease is caused by the spirochete B. burgdorferi, which is transmitted by the bite of a small tick of the genus Ixodes. Humans are “accidental” hosts for B. burgdorferi because spirochetes from infected people are not transmitted to other hosts. While in the midgut of the Ixodes tick between feeding periods, the spirochetes …

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Laboratory diagnosis, treatment and prevention of Borrelia burgdorferi

Laboratory diagnosis of Borrelia burgdorferi

Laboratory diagnosis of Borrelia burgdorferi Specimen Blood, cerebrospinal fluid, joint fluid, tissue biopsies Body fluids should be transported without any preservatives. Tissue biopsy specimens should be placed in sterile saline to prevent drying. Direct detection methods The organisms can be seen directly in wet preparations of peripheral blood (mixed with equal parts of sterile, non bacteriostatic saline) under dark- or …

Read moreLaboratory diagnosis, treatment and prevention of Borrelia burgdorferi