Bile Solubility Test- Principle, Procedure, Types, Results, Uses

Bile Solubility Test- Principle, Procedure and Result Interpretation

What is Bile Solubility Test? Bile solubility test is a biochemical test used for the differentiation and confirmation of Streptococcus pneumoniae from other alpha-hemolytic Streptococci. The bile solubility test has been used as an essential test for the differentiation of S. pneumoniae as it allows the distinction between the two species S. pneumoniae and Streptococcus pseudopneumoniae, which is a challenging task. The …

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Laboratory diagnosis, Treatment and Prevention of Streptococcus pneumoniae

Laboratory diagnosis, Treatment and Prevention of Streptococcus pneumoniae

Laboratory diagnosis of Streptococcus pneumoniae Specimen: Sputum, blood, endotracheal aspirate, bronchoalveolar lavage, cerebrospinal fluid (CSF), pleural fluid, joint fluid, abscess fluid, bones, and other biopsy material. Microscopy Gram staining of sputum shows lancet shaped Gram-positive cocci in pairs. Fresh emulsified sputum mixed with antiserum causes capsule swelling (the quellung reaction) for identification of pneumococci. In acute pneumococcal otitis media, Gram …

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