Immunoglobulin E (IgE) is one of the 5 classes of immunoglobulins, which is defined by the presence of epsilon (ε) heavy chain. It is present in circulation at very low concentrations of less than 1 µg/mL which is approximately 300-fold lower than that of IgG. Although least abundant, it is in many respects the most … Read more Immunoglobulin E (IgE)- Structure and Functions
Immunoglobulin M (IgM) is an antigen receptor on B cells and the first antibody produced in an immune response. It is present both on B cells, and as a soluble molecule in the blood. Because of its large size (900 kDa), IgM is found primarily in the intravascular space i.e. in the bloodstream and also … Read more Immunoglobulin M (IgM)- Structure and Functions
Immunization is the process whereby a person naturally acquires or is induced to acquire immunity or resistance to an infectious disease. An individual can acquire such immunity either passively or actively and thus immunization may be active or passive immunization. Passive immunization In passive immunization, a person receives antibodies or lymphocytes that have been produced by another individual’s immune system … Read more Passive immunization with advantages and drawbacks
What is Immunology? Immunology is the study of how the body responds to foreign substances and fights off infection and other disease. Immunologists study the molecules, cells, and organs of the human body that participate in this response. Immunity Immunity is a condition of being able to resist a particular disease especially through preventing the … Read more What is Immunology?
Monoclonal antibodies They are antibodies that are made by identical immune cells that are all clones of a unique parent cell. Monoclonal antibodies can have monovalent affinity, in that they bind to the same epitope. A technique to produce monoclonal antibodies was devised by Georges Kohler and Cesar Milstein in 1975. The method relies on … Read more Monoclonal Antibodies- Types, Uses and Limitations
Properties and Function of different classes of Antibodies Antibodies are glycoproteins produced in membrane-bound or secreted form by B lymphocytes in response to exposure to foreign structures known as antigens. The human immunoglobulins are a family of proteins that confer humoral immunity and perform vital roles in promoting cellular immunity. There are five classes of … Read more Properties and Function of different classes of Antibodies