14 differences between Agglutination and Precipitation

differences between Agglutination and Precipitation (Agglutination vs Precipitation)

Image Source: Biology Online and Lumen Learning. Agglutination Definition Agglutination is the process of clumping of antigens with their respective antibodies. Agglutination reactions are used to particulate test antigens that are usually conjugated to a carrier. The carrier can either be artificial (such as latex or charcoal particles) or biological (such as red blood cells). The agglutination process involving red …

Read more14 differences between Agglutination and Precipitation

Coomb’s Test- Direct and Indirect Coomb’s Test

Result Interpretation of Coomb's Test

Coomb’s Test- Direct and Indirect Coomb’s Test Coomb’s test is a direct agglutination reaction, more commonly known as antiglobulin test. It was discovered by Coombs, Mourant and Race in 1945 originally for the detection of incomplete anti-Rh antibodies. In the test, incomplete antibodies do not agglutinate erythrocytes. Incomplete antibody antiglobulin coats the surface of erythrocytes but does not cause any …

Read moreCoomb’s Test- Direct and Indirect Coomb’s Test

Types of Agglutination Reactions

Antiglobulin (Coombs) test

Types of Agglutination Reactions Agglutination reactions can be broadly divided into three groups: Active/Direct agglutination Passive agglutination Hemagglutination 1. Active agglutination Agglutination reactions where the antigens are found naturally on a particle are known as direct agglutination. In active agglutination, direct agglutination of particulate antigen with specific antibody occurs. Direct bacterial agglutination uses whole pathogens as a source of antigen. …

Read moreTypes of Agglutination Reactions

Agglutination – definition, reactions and applications

Agglutination- Introduction and Applications

Agglutination definition Agglutination is an antigen-antibody reaction in which a particulate antigen combines with its antibody in the presence of electrolytes at a specified temperature and pH resulting in the formation of visible clumping of particles. It occurs optimally when antigens and antibodies react in equivalent proportions. This reaction is analogous to the precipitation reaction in that antibodies act as …

Read moreAgglutination – definition, reactions and applications