Yeast Artificial Chromosome (YAC)

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Yeast Artificial Chromosome (YAC) definition

A genetically engineered chromosome with yeast origin of replication and centromere sequence. (Brock Biology of Microorganisms)

Engineered DNA that contains all the elements required to propagate a chromosome in yeast and is used to clone foreign DNA fragments in yeast cells. (Prescott’s Microbiology)