Rapid Plasma Reagin (RPR) Test

Rapid Plasma Reagin (RPR) Test

Rapid Plasma Reagin (RPR) like the Venereal Disease Research Laboratory (VDRL) test is a screening test for syphilis which is a sexually transmitted infection caused by the spirochete bacterium Treponema pallidum. It is a rapid non-treponemal test that looks for non-specific antibodies in the blood of the patient that may indicate a syphilis infection. The test does not look for antibodies against … Read more Rapid Plasma Reagin (RPR) Test

Coomb’s Test- Direct and Indirect Coomb’s Test

Result Interpretation of Coomb's Test

Coomb’s Test- Direct and Indirect Coomb’s Test Coomb’s test is a direct agglutination reaction, more commonly known as antiglobulin test. It was discovered by Coombs, Mourant and Race in 1945 originally for the detection of incomplete anti-Rh antibodies. In the test, incomplete antibodies do not agglutinate erythrocytes. Incomplete antibody antiglobulin coats the surface of erythrocytes … Read more Coomb’s Test- Direct and Indirect Coomb’s Test

Venereal Disease Research Laboratory (VDRL) Test

Result Interpretation of VDRL Test

The Venereal Disease Research Laboratory test (VDRL) is a screening test for sexually transmitted infection – syphilis caused by the spirochete bacterium Treponema pallidum.  It is a non-treponemal test, which detects antibodies IgM and IgG antibodies to lipoidal material released from damaged host cells as well as to lipoprotein-like material, and possibly cardiolipin released from the treponemes. These antibodies are … Read more Venereal Disease Research Laboratory (VDRL) Test